Bioactivity:

GSK840 is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which binds the RIP3 kinase domain (IC50: 0.9 nM), and inhibits kinase activity (IC50: 0.3 nM).

CAS nr:

2361146-30-5

Purity:

98%

Molecular Weight:

365,43

SMILES:

O=C(OC(C)(C)C)CC1=CC=C(N2C3=CC=C(C(NC)=O)C=C3N=C2)C=C1

Formula:

C21H23N3O3

Pathway:

NF-_b,Apoptosis

Target:

RIP kinase,RIP kinase