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Bioactivity:
GSK2334470 is a novel PDK1 inhibitor (IC50: ~10 nM, in a cell-free assay), with no inhibitory at other close related AGC-kinases.
CAS nr:
1227911-45-6
Purity:
98%
Molecular Weight:
462,59
SMILES:
CNc1nc(cc(n1)-c1ccc2c(N)n[nH]c2c1)N1C[C@H](CC[C@H]1C)C(=O)NC1CCCCC1
Formula:
C25H34N8O
Pathway:
PI3K/Akt/mTOR signaling
Target:
PDK