Bioactivity:

CH5183284 is a selective and orally available FGFR inhibitor, which is for FGFR1(IC50=9.3 nM), FGFR2(IC50=7.6 nM), FGFR3(IC50=290), and FGFR4(IC50=22 nM), respectively.

CAS nr:

1265229-25-1

Purity:

98%

Molecular Weight:

356,38

SMILES:

Cc1nc2c([nH]1)cc(cc2)n1c(c(cn1)C(=O)c1cc2ccccc2[nH]1)N

Formula:

C20H16N6O

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

FGFR,FGFR