Bioactivity:

Antihistamine-1 is an H1-antihistamine (Ki: 6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel (IC50s: 5.4 and 0.8 _M).

CAS nr:

1186430-60-3

Purity:

98%

Molecular Weight:

389,47

SMILES:

CC1=CN(C2CCN(C3=NC4=CC=CC=C4N3CC5=CC=C(F)C=C5)CC2)N=C1

Formula:

C23H24FN5

Pathway:

Metabolism

Target:

P450