JAK1-IN-4 T15606
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
JAK1-IN-4 is a selective JAK1 inhibitor (IC50s: 85 nM, 12.8 _M and >30 _M for JAK1, JAK2, and JAK3, respectively). JAK1-IN-4 inhibits STAT3 phosphorylation in NCI-H 1975 cells (IC50, 227 nM).
CAS nr:
2091134-35-7
Purity:
98%
Molecular Weight:
521,59
SMILES:
O=C(NC1=CC=CC2=C1NC=C2C3=C(C=NC(NC4=CN(N=C4OC)C)=N3)F)[C@H](N5CCN([C@@H](C5)C)C)C
Formula:
C26H32FN9O2
Pathway:
JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells,Angiogenesis
Target:
JAK,JAK,JAK,JAK
Since their establishment in the United States in 2008, they have been working in the field of biotechnology for more than 10 years. With the increase in product portfolio and the shift in production focus, they are now located in Taiwan.