Bioactivity:

CBL0137 activates p53 and inhibits NF-kB (EC50: 0.37/0.47 _M) in the cell-based p53 and NF-kB reporter assays, respectively. It also suppresses histone chaperone FACT.

CAS nr:

1197397-89-9

Purity:

98%

Molecular Weight:

372,88

SMILES:

CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C.Cl

Formula:

C21H25ClN2O2

Pathway:

Others,NF-_b,Apoptosis

Target:

Others,NF-_B,p53