Bioactivity:

(Z)-Guggulsterone inhibits the growth of human prostate cancer cells by causing apoptosis. Z-guggulsterone inhibits angiogenesis by suppressing the VEGF�VEGF-R2�Akt signaling axis.

CAS nr:

39025-23-5

Purity:

98%

Molecular Weight:

312,45

SMILES:

C/C=C/1\C(=O)C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C

Formula:

C21H28O2

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,Apoptosis

Target:

VEGFR,VEGFR,Akt,Akt,Apoptosis