Bioactivity:

JY-1-106 is a BH3 _-helix mimetic, inducing apoptosis in a subset of cancer cells (lung cancer, colon cancer and mesothelioma) by disrupting Bcl-xL and Mcl-1 protein-protein interactions with Bak.

CAS nr:

T32344

Purity:

98%

Molecular Weight:

550,61

SMILES:

O=C(O)C1=CC=C(NC(C2=NC(OC(C)C)=C(NC(C3=CC=C(N)C(OC(C)C)=C3)=O)C=C2)=O)C(OC(C)C)=C1

Formula:

C29H34N4O7

Pathway:

Target: