A-740003 T3690
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
A 740003 is an effective and specific P2X7�receptor antagonist (IC50: 18/40 nM, for rat/human). It can reduce nociception in animal models of persistent neuropathic and inflammatory pain, and also reduce neuroblastoma tumor growth in mice.
CAS nr:
861393-28-4
Purity:
98%
Molecular Weight:
474,55
SMILES:
COc1ccc(CC(=O)NC(N\C(Nc2cccc3ncccc23)=N\C#N)C(C)(C)C)cc1OC
Formula:
C26H30N6O3
Pathway:
Membrane transporter/Ion channel,Neuroscience
Target:
P2X Receptor,P2 Receptor
