Bioactivity:

Isosilybin A is a partial PPAR_ agonist, it significantly induced ABCA1 protein expression, it inhibited both monophenolase (IC50=1.7-7.6_M) and diphenolase (IC50=12.1-44.9_M) of tyrosinase. Isosilybin A shows anti-angiogenic efficacy, it has anti-prostat

CAS nr:

142796-21-2

Purity:

98%

Molecular Weight:

482,44

SMILES:

COc(cc([C@H]1Oc(ccc([C@H]([C@H](C2=O)O)Oc3c2c(O)cc(O)c3)c2)c2O[C@@H]1CO)cc1)c1O

Formula:

C25H22O10

Pathway:

Metabolism,DNA Damage/DNA Repair,Apoptosis,Proteases/Proteasome,Membrane transporter/Ion channel

Target:

PPAR,PPAR,Apoptosis,Tyrosinase,ABC