Bioactivity:

GDC-0834 inhibits BTK with an in vitro IC50 of 5.9 and 6.4 nM in biochemical and cellular assays, respectively, and in vivo IC50 of 1.1 and 5.6 _M in mouse and rat, respectively.�GDC-0834 is a potent and selective BTK inhib

CAS nr:

1133432-49-1

Purity:

98%

Molecular Weight:

596,74

SMILES:

O=C(C1=CC(CCCC2)=C2S1)NC3=CC=CC(C(N=C4NC5=CC=C([C@H]6N(C)CCN(C)C6=O)C=C5)=CN(C)C4=O)=C3C

Formula:

C33H36N6O3S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK