Softsubstrates MUWells

Cells cultured in vitro on substrates of physiological rigidity were documented to resemble physiology of cells in vivomuch better than cells grown on flat plastic surfaces of traditional tissue culture plates. Softsubstrates™ plates are our simple and elegant tools to culture cells on substrates of defined rigidities. On the bottom of each well is a thin layer of specially formulated biocompatible elastomer which rigidity is measured and certified for producing successful repeat experiments. Advantages of our SoftSubstrates™ Cell Culture Products:
• Seven rigidities of SoftSubstrates™ coating effectively cover physiological range of soft tissues.
• Elastic coating of SoftSubstrates™ is made of silicone gel which neither hydrolyze nor bio-degrade.
• SoftSubstrates™ coating is transparent and has low auto-fluorescence. • Cell culture surface of SoftSubstrates™ is functionalized for reagent-free coating with matrix proteins.
• SoftSubstrates™ are ozone sterilized with at least one year of shelf life. • Elastic modulus of the coating is measured for each production batch.

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TargetMol Chemicals

TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

www.targetmol.com

The prices are on request! Contact Us by e-mail info@sobekbio.com

Beaver

BEAVER was founded in 2011, BEAVER focuses on magnetic beads technology and industrialized production, serving in vitro diagnosis, bio-pharmaceuticals, animal disease detection, environmental testing, food and drug safety testing, biological scientific research and other fields.

BEAVER provides commercial magnetic beads, including pre-activated magnetic beads Immunolabeling and capture magnetic beads, nucleic acid extraction magnetic beads and kits, mycotoxin purification kits and other products, as well as auxiliary automation equipment and supporting biological consumables.
www.beavermagbeads.com

DIMA Biotech

DIMA Biotechnology Ltd. is a biotech company focusing on preclinical R&D products and services for druggable targets. They plan to complete the preparation of lead antibody molecules for all druggable targets in the next 3-5 years. DIMA Biotech provides multiple pre-prepared lead antibody molecules for each target to help pharmaceutical companies skip the tedious steps of monoclonal antibody platform establishment and lead molecule screening. Therefore, companies can have more time to focus on the biological mechanism and developability study of drug targets, thus accelerating the process of new drug R&D.

Over the years, DIMA Biotech has been deeply engaged in developing and optimizing the underlying technology platforms for preclinical research. Currently, they have established two independently developed core technology platforms:

Single/multiple transmembrane protein eukaryotic expression, preparation and purification platforms, apply mammalian cell expression systems, provide ECD or full-length membrane protein products closest to native conformation and functional validation. In addition, DIMA Biotech has developed five major functional full-length transmembrane protein preparation systems, including Membrane Nanoparticle (MNP), Virus-Like Particle (VLP), Exosome (EXO), Detergent and Synthetic Nanodisc. Thousands of drug target protein products are in stock.
DimAb® High-throughput single B-cell lead antibody molecule discovery platform. DIMA Biotech has completed the preparation and screening of lead antibody molecules against more than 200 drug targets by this platform in just two years. Moreover, they have formed strategic partnerships with several international pharmaceutical enterprises and licensed several drug target molecules. DIMA’s preclinical development strength is widely recognized by the industry.

www.dimabio.com

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Pictilisib T1994

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Pictilisib (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110_/_/_/_).

CAS nr:

957054-30-7

Purity:

98%

Molecular Weight:

513,64

SMILES:

CS(=O)(=O)N1CCN(Cc2cc3nc(nc(N4CCOCC4)c3s2)-c2cccc3[nH]ncc23)CC1

Formula:

C23H27N7O3S2

Pathway:

PI3K/Akt/mTOR signaling,Autophagy,Apoptosis

Target:

PI3K,Autophagy,Apoptosis