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JAK2/FLT3-IN-1 T11707
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
JAK2/FLT3-IN-1 has anti-cancer activity. JAK2/FLT3-IN-1 is a potent and orally effective dual JAK2/FLT3 (Janus kinase 2/ FMS-like tyrosine kinase 3) inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively.
CAS nr:
2387765-27-5
Purity:
98%
Molecular Weight:
467,58
SMILES:
OCCN(C1CCN(C2=CC=C(NC3=NC=C(C)C(C4=CN(C(C)C)N=C4)=N3)C=C2F)CC1)C
Formula:
C25H34FN7O
Pathway:
MAPK
Target:
JNK