Bioactivity:

JTE-013 is an effective and specific antagonist of S1P2. JTE-013 suppresses the specific binding of radiolabeled S1P to human and rat S1P2 (IC50s: 17 nM and 22 nM, respectively).

CAS nr:

383150-41-2

Purity:

98%

Molecular Weight:

408,29

SMILES:

CC(C1=C2C(N(C)N=C2C)=NC(NNC(NC3=CC(Cl)=NC(Cl)=C3)=O)=C1)C

Formula:

C17H19Cl2N7O

Pathway:

GPCR/G Protein,GPCR/G Protein,Apoptosis

Target:

S1P Receptor,LPL Receptor,Apoptosis