E 2012 T15184
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
E2012 is a _-secretase modulator (GSM).�E2012 inhibits 3_-hydroxysterol _24-reductase (DHCR24) at the final step in the cholesterol biosynthesis.�E 2012 aims at Alzheimer's disease by reduction of amyloid _-42, and induces cataract following repeated dose
CAS nr:
870843-42-8
Purity:
98%
Molecular Weight:
419,49
SMILES:
O=C1N([C@H](C2=CC=C(F)C=C2)C)CCC/C1=C\C3=CC=C(N4C=C(C)N=C4)C(OC)=C3
Formula:
C25H26FN3O2
Pathway:
Stem Cells,Proteases/Proteasome,Neuroscience
Target:
Gamma-secretase,Gamma-secretase,Gamma-secretase
