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Bioactivity:
IRAK inhibitor 1 is an effective IRAK-4 inhibitor (IC50: 216 nM), is poorly active against JNK-1 (IC50: 3.801 _M) and JNK-2 (IC50>10 _M).
CAS nr:
1042224-63-4
Purity:
98%
Molecular Weight:
293,37
SMILES:
C1CC(CCN1)Nc1cccc(n1)-c1cnc2ccccn12
Formula:
C17H19N5
Pathway:
MAPK,NF-_b,Immunology/Inflammation
Target:
JNK,IRAK,IRAK