Bioactivity:

Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition.

CAS nr:

165668-41-7

Purity:

98%

Molecular Weight:

385,85

SMILES:

C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N)NC=C2Cl

Formula:

C14H12ClN3O4S2

Pathway:

Metabolism,Cell Cycle/Checkpoint

Target:

Carbonic Anhydrase,CDK