Bioactivity:

Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM).

CAS nr:

184475-35-2

Purity:

98%

Molecular Weight:

446,91

SMILES:

COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCOCC1

Formula:

C22H24ClFN4O3

Pathway:

Tyrosine Kinase/Adaptors,Autophagy,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

Tyrosine Kinases,Autophagy,EGFR,EGFR,EGFR