Bioactivity:

PF-06767832 is a high quality M1 selective PAM (M1 PAM EC50 = 60 nM; M2-M5 PAM EC50 > 10 microM; CNS MPO = 4.9). PF-06767832 has well aligned physicochemical properties, good brain penetration and pharmacokinetic properties. Extensive safety profiling

CAS nr:

1859081-58-5

Purity:

98%

Molecular Weight:

409,5

SMILES:

O=C(C1=NC=C(C)C(CC2=CC=C(C3=CSC=N3)C=C2)=C1)N[C@@H]4[C@@H](O)COCC4

Formula:

C22H23N3O3S

Pathway:

Target: