Bioactivity:

INCB054329, a structurally distinct bromodomain and extraterminal domain (BET) inhibitor, inhibits BRD2-BD1, BRD2-BD2, BRD3-BD1, BRD3-BD2, BRD4-BD1, BRD4-BD2, BRDT-BD1 and BRDT-BD2 with IC50 values of 44 nM, 5 nM, 9 nM, 1 nM, 28 nM, 3 nM, 119 nM and 63 nM

CAS nr:

1628607-64-6

Purity:

98%

Molecular Weight:

348,36

SMILES:

CC1=C(C(=NO1)C)C2=CC=C3NC(=O)N4C(COC2=C34)C5=NC=CC=C5

Formula:

C19H16N4O3

Pathway:

Others,Chromatin/Epigenetic

Target:

Others,Epigenetic Reader Domain