Bioactivity:

SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively).

CAS nr:

1226917-67-4

Purity:

98%

Molecular Weight:

511,49

SMILES:

O=C(C1=CC=NC2=CC=CC=C12)N[C@H]3CC[C@H](CCN4CC5=C(C=C(C#N)C=C5)CC4)CC3.[H]Cl.[H]Cl

Formula:

C28H32Cl2N4O

Pathway:

Neuroscience,GPCR/G Protein

Target:

Dopamine Receptor,Dopamine Receptor