Bioactivity:

TAK-220 is a selective and orally bioavailable CCR5 antagonist (IC50s: 3.5 nM and 1.4 nM for inhibition on the binding of RANTES and MIP-1_ to CCR5, respectively).

CAS nr:

333994-00-6

Purity:

98%

Molecular Weight:

553,14

SMILES:

O=C(C1CCN(C(C)=O)CC1)N(CCCN2CCC(CC3=CC=C(C(N)=O)C=C3)CC2)C4=CC=C(C)C(Cl)=C4

Formula:

C31H41ClN4O3

Pathway:

Proteases/Proteasome,Microbiology/Virology

Target:

HIV Protease,HIV Protease