Bioactivity:

Cimiside E has anti-inflammatory activity, it selectively inhibits TNF-_-induced expression of VCAM-1 at least by upregulation of PPAR-_, and signals for ERK1/2, PI3K, and PKC are involved in this effect.Cimiside E may be an effective chemopreventive agen

CAS nr:

154822-57-8

Purity:

98%

Molecular Weight:

602,8

SMILES:

C[C@@H]1C[C@H]2O[C@@]3(O[C@H]2C(C)=C)[C@@H](O)[C@@]2(C)[C@@H]4CC[C@@H]5[C@]6(CC46CC[C@]2(C)C13)CC[C@@H](O[C@@H]1OC[C@@H](O)[C@H](O)[C@H]1O)C5(C)C

Formula:

C35H54O8

Pathway:

Cytoskeletal Signaling,Chromatin/Epigenetic,Apoptosis,Immunology/Inflammation,PI3K/Akt/mTOR signaling,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,DNA Damage/DNA Repair,Metabolism,MAPK

Target:

PKC,PKC,TNF,ROS,PI3K,Akt,Akt,PPAR,PPAR,ERK