Bioactivity:

CH6953755 is a potent, orally active and selective inhibitor of YES1 kinase (IC50: 1.8 nM). It inhibits YES1 kinase, leading to antitumor activity against YES1 Gene -amplified cancers in vitro and in vivo.

CAS nr:

2055918-71-1

Purity:

98%

Molecular Weight:

552,55

SMILES:

CS(=O)(NC1=CC2=C(C=C1C)C=C(C(C3=C(N)N(C4=C(C)C=C(OC5=C(F)C=CC=C5F)N=C4)N=C3)=O)N2)=O

Formula:

C26H22F2N6O4S

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis

Target:

Src,Src