Bioactivity:

RG-12525 is a PPAR-gamma agonist (IC50: appr 60 nM) and a potent inhibitor of CYP3A4 (Ki: 0.5 ﾵM). RG-12525 is a specific and competitive antagonist of the peptidoleukotrienes, LTC4, LTD4, and LTE4, inhibiting LTC4-, LTD4- and LTE4-induced guinea pig pare

CAS nr:

120128-20-3

Purity:

98%

Molecular Weight:

423,47

SMILES:

C1(COC2=CC=C(OCC3=CC=CC=C3CC4=NN=NN4)C=C2)=NC5=CC=CC=C5C=C1

Formula:

C25H21N5O2

Pathway:

Metabolism,Metabolism,DNA Damage/DNA Repair

Target:

P450,PPAR,PPAR