Bioactivity:

BAZ2-ICR is an epigenetic chemical probe and it also is a potent, selective, cell active and orally active BAZ2A/B bromodomains inhibitor with IC50s of 130 nM and 180 nM, and Kds of 109 nM and 170 nM, respectively. BAZ2-ICR shows 10-15-fold selectivity fo

CAS nr:

1665195-94-7

Purity:

98%

Molecular Weight:

357,41

SMILES:

N#CC1=CC=C(C2=C(C3=CN(C)N=C3)N=CN2CCC4=CN(C)N=C4)C=C1

Formula:

C20H19N7

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain