Bioactivity:

MKC8866 is a selective IRE1 RNase inhibitor (IC50: 0.29__M in human vitro). MKC8866 inhibits IRE1 RNase in breast cancer cells leading to the decreased production of pro-tumorigenic factors and it can inhibit prostate cancer (PCa) tumor growth.

CAS nr:

1338934-59-0

Purity:

98%

Molecular Weight:

361,35

SMILES:

O=CC1=C(O)C(OC)=CC2=C1OC(C(CC(N3CCOCC3)=O)=C2C)=O

Formula:

C18H19NO7

Pathway:

Cell Cycle/Checkpoint

Target:

IRE1