Bioactivity:

Sunitinib, a multi-targeted RTK inhibitor, is targeting PDGFR_ and VEGFR2 (Flk-1) with IC50 of 2 nM and 80 nM and also inhibits c-Kit.

CAS nr:

557795-19-4

Purity:

98%

Molecular Weight:

398,47

SMILES:

CCN(CC)CCNC(=O)c1c(C)[nH]c(/C=C/2\C(=O)Nc3c2cc(F)cc3)c1C

Formula:

C22H27FN4O2

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Autophagy,Cell Cycle/Checkpoint,Apoptosis,Autophagy,Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR,VEGFR,VEGFR,Autophagy,IRE1,Apoptosis,Mitophagy,FLT,FLT,c-Kit