Bioactivity:

BGB-290 is an orally active, potent, highly selective PARP inhibitor(IC50 of 0.9 nM and 0.5 nM for PARP1 and PARP2, respectively). It has potent PARP trapping, and capability to penetrate the brain, and can be used for the research of various cancers incl

CAS nr:

1446261-44-4

Purity:

98%

Molecular Weight:

298,31

SMILES:

C[C@]12CCCN1CC3=NNC(=O)C4=C5C3=C2NC5=CC(=C4)F

Formula:

C16H15FN4O

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

PARP,PARP