Bioactivity:

Pelitinib (EKB-569) is an effective irreversible EGFR inhibitor (IC50: 38.5 nM).

CAS nr:

257933-82-7

Purity:

98%

Molecular Weight:

467,92

SMILES:

CCOc1c(cc2c(c1)ncc(c2Nc1cc(c(cc1)F)Cl)C#N)NC(=O)/C=C/CN(C)C

Formula:

C24H23ClFN5O2

Pathway:

MAPK,MAPK,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

Raf,MEK,Src,Src,EGFR,EGFR,EGFR