Bioactivity:

Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of HUVEC in a dose-dependent manner, it has shown meaningful angiogenesis activity. Taspine exhibi

CAS nr:

602-07-3

Purity:

98%

Molecular Weight:

369,37

SMILES:

COc1ccc2c3c1oc(=O)c1c(CCN(C)C)cc(OC)c(oc2=O)c31

Formula:

C20H19NO6

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,MAPK,Apoptosis,Cytoskeletal Signaling,PI3K/Akt/mTOR signaling,JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis,MAPK

Target:

VEGFR,VEGFR,MAPK,BCL,Akt,Akt,EGFR,EGFR,EGFR,ERK