Bioactivity:

MONNA is a potent TMEM16A (Anoctamin-1) blocker (IC50 : 80 nM). It induces vasorelaxation of rodent resistance arteries in presence or absence of chloride ions.

CAS nr:

1572936-83-4

Purity:

98%

Molecular Weight:

338,31

SMILES:

COC1=CC(=CC2=CC=CC=C21)NC3=C(C=C(C=C3)[N+](=O)[O-])C(=O)O

Formula:

C18H14N2O5

Pathway:

Membrane transporter/Ion channel

Target:

Chloride channel