Bioactivity:

Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 _M). The Timosaponin AIII cellular response is mediated via inhibition of mTORC1 and induction of ER stress (IC50: 2.5 _M, BT474 cells; 6 _M, MDAMB231). The Timosa

CAS nr:

41059-79-4

Purity:

98%

Molecular Weight:

740,92

SMILES:

C[C@H]1[C@H]2[C@H](C[C@H]3[C@@H]4CC[C@@H]5C[C@H](CC[C@]5(C)[C@H]4CC[C@]23C)O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)O[C@]11CCC(C)CO1

Formula:

C39H64O13

Pathway:

Neuroscience,PI3K/Akt/mTOR signaling

Target:

AChE,mTOR