Bioactivity:

PI-1840_ IC50 = 27 nM_is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L).

CAS nr:

1401223-22-0

Purity:

98%

Molecular Weight:

394,47

SMILES:

CCCc1ccc(OCC(=O)N(Cc2nc(no2)c2cccnc2)C(C)C)cc1

Formula:

C22H26N4O3

Pathway:

Proteases/Proteasome,Ubiquitination

Target:

Proteasome,Proteasome