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Bioactivity:
MK-8745 is a potent and selective Aurora A inhibitor.
CAS nr:
885325-71-3
Purity:
98%
Molecular Weight:
431,91
SMILES:
C1CN(CCN1Cc1nc(ccc1)Nc1nccs1)C(=O)c1c(c(ccc1)Cl)F
Formula:
C20H19ClFN5OS
Pathway:
Cell Cycle/Checkpoint,Chromatin/Epigenetic,Apoptosis
Target:
Aurora Kinase,Aurora Kinase,Apoptosis