Bioactivity:

Zotarolimus, an analogue of rapamycin, inhibits FKBP-12 (IC50= 2.8 nM).

CAS nr:

221877-54-9

Purity:

98%

Molecular Weight:

966,21

SMILES:

[H][C@@]12CCCCN1C(=O)C(=O)[C@]1(O)O[C@@H](CC[C@H]1C)C[C@H](OC)\C(C)=C\C=C\C=C\[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)\C(C)=C\[C@@H](C)C(=O)C[C@H](OC2=O)[C@H](C)C[C@@H]1CC[C@@H]([C@@H](C1)OC)N1C=NN=N1

Formula:

C52H79N5O12

Pathway:

PI3K/Akt/mTOR signaling

Target:

mTOR