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Bioactivity:
DS-437 is a dual PRMT5/7 inhibitor (IC50s: 6 _M). DS-437 also inhibits DNMT3A and DNMT3B (IC50s: 52 and 62 _M). DS-437 inhibits the methylation of FOXP3.
CAS nr:
1674364-87-4
Purity:
98%
Molecular Weight:
397,45
SMILES:
O[C@@H]([C@H]([C@H](N1C=NC2=C(N=CN=C21)N)O3)O)[C@H]3CSCCNC(NCC)=O
Formula:
C15H23N7O4S
Pathway:
Others
Target:
Others