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Rigosertib sodium T5818

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Rigosertib, a non-ATP-competitive inhibitor of PLK1(IC50=9 nM), exhibits 30-fold higher specificity activity over Plk2 and no effect on Plk3.

CAS nr:

592542-60-4

Purity:

98%

Molecular Weight:

473,47

SMILES:

COc1c(cc(cc1)CS(=O)(=O)/C=C/c1c(cc(cc1OC)OC)OC)NCC(=O)[O-].[Na+]

Formula:

C21H24NNaO8S

Pathway:

PI3K/Akt/mTOR signaling,Cell Cycle/Checkpoint,Apoptosis

Target:

PI3K,PLK,Apoptosis