Bioactivity:

Palbociclib D8 is a deuterium labeled Palbociclib. Palbociclib is a selective and orally active inhibitor of CDK4 and CDK6 (IC50s of 11 and 16 nM, respectively).

CAS nr:

1628752-83-9

Purity:

98%

Molecular Weight:

455,58

SMILES:

O=C1N(C2=NC(NC3=NC=C(C=C3)N4C([2H])(C([2H])(NC([2H])(C4([2H])[2H])[2H])[2H])[2H])=NC=C2C(C)=C1C(C)=O)C5CCCC5

Formula:

C24H21D8N7O2

Pathway:

Cell Cycle/Checkpoint

Target:

CDK