Bioactivity:

APX-115 (Ewha-18278) is a potent, orally active pan NADPH oxidase _Nox) inhibitor (Kis: 1.08 _M, 0.57 _M, and 0.63 _M for Nox1, Nox2, and Nox4). APX-115 effectively prevents kidney injury.

CAS nr:

1395946-75-4

Purity:

98%

Molecular Weight:

315,8

SMILES:

OC1=C(CCC)C(C2=CC=CC=C2)=NN1C3=NC=CC=C3.Cl

Formula:

C17H18ClN3O

Pathway:

Immunology/Inflammation

Target:

NADPH-oxidase