Bioactivity:

Jaspamycin (7-CN-7-C-Ino) does not bind with purified human PKARI_. Anti-parasite activity. Jaspamycin (7-CN-7-C-Ino) is a potent activator of PKA, binding to the R site (PKAR), with an EC50 of 6.5 nM and Kd of 8 nM in Trypanosoma brucei.

CAS nr:

22242-96-2

Purity:

98%

Molecular Weight:

292,25

SMILES:

O=C1C2=C(N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=C2C#N)N=CN1

Formula:

C12H12N4O5

Pathway:

Stem Cells,Angiogenesis,JAK/STAT signaling,Chromatin/Epigenetic

Target:

JAK,JAK,JAK,JAK