Bioactivity:

Cdc7-IN-1 is a highly selective and ATP competitive inhibitor of Cdc7 kinase (IC50: 0.6 nM at 1 mM ATP). It potently inhibits Cdc7 activity in cancer cells and effectively induces cell death.

CAS nr:

1402055-25-7

Purity:

98%

Molecular Weight:

409,82

SMILES:

O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=C\C3=CNC4=C3C=CC=N4

Formula:

C21H16ClN3O4

Pathway:

Cell Cycle/Checkpoint

Target:

CDK