Bioactivity:

Cl-amidine hydrochloride is an orally active peptidylarginine deminase (PAD) inhibitor (IC50: 5.9 _M for PAD4). Cl-amidine hydrochloride induces apoptosis in cancer cells and it also induces microRNA (miR)-16 in vitro causing cell cycle arrest. Cl-Amidine

CAS nr:

1373232-26-8

Purity:

98%

Molecular Weight:

347,24

SMILES:

O=C(N[C@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1.[H]Cl

Formula:

C14H20Cl2N4O2

Pathway:

Chromatin/Epigenetic,Apoptosis

Target:

PAD,Apoptosis