Bioactivity:

Pazopanib, a small molecule inhibitor, inhibits multiple protein tyrosine kinases with potential antineoplastic activity. Pazopanib selectively inhibits VEGFR-1, -2 and -3, c-kit and PDGF-R, which may result in inhibition of angiogenesis in tumors in whic

CAS nr:

444731-52-6

Purity:

98%

Molecular Weight:

437,52

SMILES:

CN(c1cc2nn(C)c(C)c2cc1)c1nc(Nc2cc(c(C)cc2)S(=O)(=O)N)ncc1

Formula:

C21H23N7O2S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors,Angiogenesis,Autophagy,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR,VEGFR,VEGFR,FGFR,FGFR,Autophagy,c-Kit