Bioactivity:

DYRKs-IN-1 has antitumor activity.�DYRKs-IN-1 is a potent DYRKs (Dual-specificity tyrosine-phosphorylation-regulated kinases) inhibitor with IC50s of 9 nM and 5 nM for DYRK1B and DYRK1A, respectively.

CAS nr:

1387090-01-8

Purity:

98%

Molecular Weight:

588,06

SMILES:

O=C(C1=CC2=CN=C(N3CC(O4)CCC4C3)N=C2NC1=O)NC5=CC(C(NC(C6=CC=CC=C6)CCN)=O)=CC=C5Cl

Formula:

C30H30ClN7O4

Pathway:

Tyrosine Kinase/Adaptors,Cell Cycle/Checkpoint

Target:

DYRK,DYRK