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Bioactivity:
SB-525334 is a potent and selective inhibitor of the TGF-_1R and ALK5 (IC50: 14.3 nM).
CAS nr:
356559-20-1
Purity:
98%
Molecular Weight:
343,42
SMILES:
Cc1cccc(n1)-c1[nH]c(nc1-c1ccc2nccnc2c1)C(C)(C)C
Formula:
C21H21N5
Pathway:
Stem Cells,Tyrosine Kinase/Adaptors,Angiogenesis
Target:
TGF-beta/Smad,ALK,ALK