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Bioactivity:
CRTH2-IN-1 is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist, a Ramatroban analog, with an IC50 of 6 nM in the human DP2 binding assay.
CAS nr:
926661-54-3
Purity:
98%
Molecular Weight:
416,47
SMILES:
O=C(O)CC1=C(CCC(N(S(=O)(C2=CC=C(F)C=C2)=O)C)C3)N3C4=C1C=CC=C4
Formula:
C21H21FN2O4S
Pathway:
Metabolism
Target:
P450