Bioactivity:

ProTAME is an inhibitor of APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, doxorubicin and etoposide, significantly increase cell death in primary cells and Multiple Myeloma (MM) cell lines, particularly if TOPII_ levels ar

CAS nr:

1362911-19-0

Purity:

98%

Molecular Weight:

726,75

SMILES:

O=C(OCOC(/N=C(NCCC[C@H](NS(C1=CC=C(C)C=C1)(=O)=O)C(OC)=O)/NC(OCOC(CC2=CC=CC=C2)=O)=O)=O)CC3=CC=CC=C3

Formula:

C34H38N4O12S

Pathway:

Target: