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Bioactivity:
GNE 2861 inhibits PAK4, PAK5, and PAK6 (IC50s: 7.5, 36, 126 nM, respectively). GNE 2861 is a PAK inhibitor that shows group II selectivity.
CAS nr:
1394121-05-1
Purity:
98%
Molecular Weight:
406,48
SMILES:
OC1(C#CC2=CC=C3N=C(NCCOC)N(C4=NC(N)=NC=C4)C3=C2)CCCCC1
Formula:
C22H26N6O2
Pathway:
Cytoskeletal Signaling
Target:
PAK