Bioactivity:

N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively[1]. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620 (HY-133137). SJF620 is a p

CAS nr:

330785-90-5

Purity:

98%

Molecular Weight:

SMILES:

Formula:

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK